Mariusz Jaremko, MSc.

 

 

Education:

 

1999-2003: 7th Secondary School in Wrocław (majors in chemistry and biology);
2003: Fellowship at the Organic Chemistry Institute of Polish Academy of Sciences at the prof. Mieczysław Mąkosza laboratory, Warsaw, Poland (3 weeks);

 

2003: Participant of the 1st International Science Camp in Goettingen, Germany (20.07.03 – 15.08.03), 3 week courses on Electrophysiology, Molecular Biology and Organic Chemistry;

 

2003-present: Interdisciplinary Individual Studies at the Wrocław University, Wroclaw, Poland (Departments of Chemistry, Physics and Natural Sciences);

 

2005: Fellowship at the Institute of Biochemistry and Biophysics of Polish Academy of Sciences in prof. Andrzej Ejchart laboratory, Warsaw, Poland;

 

2007-2008: Fellowship at The Scripps Research Institute at the Molecular Biology Department, prof. Kurt Wuethrich laboratory, La Jolla, USA.

 

 

 

Honors:

 

l     Finalista of the XLVII Polish National Chemistry Olympiad (00/01);

 

l     Finalista of the XLVIII Polish National Chemistry Olympiad (01/02);

 

l     Laureat of the XLIX Polish National Chemistry Olympiad (02/03);

 

l     Scholarship of the Polish Ministry of Sport and Education, 2001/02;

 

l     Scholarship of the Polish Children’s Fund, 2001/02;

 

l     Scholarship of the Polish Children’s Fund, 2002/03;

 

l     Scholarship of the Polish Ministry of Sport and Education, 2001/02;

 

l     Scholarship of the Polish Ministry of Sport and Education, 2002/03;

 

l     Scholarship of the President of my home city Wrocław, 2003/2004;

 

l     „School’s Nobel” – Scholarship of the Sitting Council of the city of Wrocław, 2003;

 

l     Laureat (1st award) on the Polish Eliminations of the 15th European Union Contest of Young Scientists, 2003;

 

l     2nd award on the 15th European Union contest for young Scientists, Budapest, 2003;

 

l     Scholarship of the Polish Ministry of Sport and Education, 2004/05;

 

l     Scholarship of the Polish Ministry of Sport and Education, 2005/06;

 

l     Scholarship of the Polish Ministry of Sport and Education, 2006/07;  

 

Publications:

 

  • Stefanowicz, P., Jaremko, L., Jaremko, M., Lis, T. (2005) Acta Cryst. E61, o1326-o1328
  • Stefanowicz, P., Jaremko, L., Jaremko, M., Lis, T. (2006) New J. Chem. 30, 258-265
  • Bryndal, I., Jaremko, M., Jaremko, L., Lis, T. (2006) Acta Cryst. C62, o111-o114
  • Jaremko L., JaremkoM., FilipekR., WojciechowskiM., SzczepanowskiR. H., BochtlerM., Zhukov I. (2006) J. Biomol. NMR. 36, 43
  • Stefanowicz, P., Jaremko, L., Jaremko, M., Staszewska, A., Szewczuk, Z., Bryndal, I., Lis, T. (2006) Acta Cryst. E62, o3555-o3557
  • Stefanowicz, P., Jaremko, L., Jaremko, M., Lis, T. (2007) Acta Cryst. E63, o1336-o1338
  • Stefanowicz, P., Jaremko, M., Jaremko, L., Kochel, A. (2007) Acta Cryst. C63, o204-o206
  • Stefanowicz, P., Jaremko, M., Jaremko, L., Lis, T. (2007) Acta Cryst. E63, o3431

 

 

 

Ubiquitin, The Molecule of The Month, September 2004,  (http://www.chem.uni.wroc.pl/jaremko/ubiquitin.htm );

 

 

 

Scientific Interests

 

- structural bioorganic chemistry: with the help of X-ray crystallography I try to understand the structural-activity relationships of aryl/alkyl-sulfonyl-N-oxyimides. Anomalous structural features found in the series of these compounds in the solid state are studied in the light of their specific chemical reactivity and biological activity. Understanding of these relationships might be useful in the design of the suicide protease inhibitors.

 

- protein structure determination by the NMR spectroscopy techniques.

 

 

 

Among others:

 

 

 

-         ancient history of the Near and Middle East (especially the hellenistic period) and Roman Empire (especially the imperial period);

 

-          Linux;

 

 

 

Languages:

 

Polish – native

 

English – proficient

 

German – good

 

 

 

Conferences and seminars:

 

  1. 18 Polish Peptide Symposium, 4-8 of September 2005, Wrocław, (2 posters: „X-ray studies of Fmoc-Phe(4-NHAc-3-NO2)-OH - a novel intermediate in the direct solid phase synthesis of quinoxaline-containing peptides” and „N-arylsulfonyl-oxysuccinimides: substrates of one-step synthesis of core N-protected albizine peptidomimetics.”);
  2. 3rd YoungChem Conference, 12-16 of October 2005, Rydzyna, (poster and Power Point presentation, ”Crystal structures of p-toluenesulfonates of N-oxyimides - the possible structural bases of serine proteases inhibition”);
  3. II Symposium: "Nuclear Magnetic Resonance in Chemistry, Biology and Medicine", 8-10 of September 2005, Warszawa, (1st award for the best poster presentation: „Przypisanie sekwencji domeny katalitycznej białka ze szlaku ubikwitylacji”);
  4. XXXVIII Ogólnopolskie Seminarium na Temat MRJ Jego Zastosowań – 1-2 of December 2005, Kraków, (1st award for the best poster presentation: „Sequence specific assignment of the First Catalytic Half Domain of E1 protein and its secondary structure”);
  5. Wiosenny Zjazd Sekcji Studenckiej PTChem, – 5-8 of April 2006, Święta Katarzyna, (poster: „Krystaliczne struktury p-toluenosulfonowych N- hydroksysukcynoimidów – próba powiązania cech strukturalnych z obserwowanymi właściwościami inhibitorowymi wobec proteaz serynowych”).
  6. 2nd NMR Workshop ‘’From data to Structure’’ & Bruker MNR users Meeting - 27-28 of June 2006, Wrocław, (poster: ‘’The three-dimensional structure of a structurally uncharacterized fragment of recombinant mouse ubiquitin-activating enzyme E1 as determined by NMR spectroscopy’’).
  7. XXIIND International Conference on Magnetic Resonance in Biological Systems – 20 – 25 of August 2006, Goettingen (Germany), (poster: “The three-dimensional structure of a structurally uncharacterised fragment of recombinant mouse ubiquitin-activating enzyme E1 as determined by NMR spectroscopy”);
  8. 4th YoungChem Conference, 25 – 29 of October 2006, Pułtusk, (poster: “The three-dimensional structure of a structurally uncharacterised fragment of recombinant mouse ubiquitin-activating enzyme E1 as determined by NMR spectroscopy”);
  9. Wiosenny Zjazd Sekcji Studenckiej PTChem, – 18-22 of April 2007, Tylmanowa, (poster: „Crystal state, solution state and gas phase studies on sulfonic esters of  N-oxyimides - looking for the nitrogen geometry...”).
  10. 2nd European Conference on Chemistry for Life Sciences, 2007 – 4-8 of September (poster: Application of random sampling NMR spectroscopy for assignments and structural determination of peptidyl-prolyl isomerase CsPin).

 

 

 

Extracuricullar activities:

 

Cooperation with Polish Children's Fund – arrangement of Research Workshops for talented Polish youth – since march 2004.

 

 

 

 

 

Additional information