Application of betain analogues for ultra-sensitive detection of peptides in OBOC strategy
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Bąchor R., Cydzik M., Rudowska M., Kluczyk A., Stefanowicz P., Szewczuk Z., Sensitive electrospray mass spectrometry analysis of one-bead-one-compound peptide libraries labeled by quaternary ammonium salts. Mol. Divers., 2012, 16, 613-618.
Bąchor R., Rudowska M., Cydzik M., Wojewska D., Kluczyk A., Stefanowicz P., Szewczuk Z., Peptides labeled by quaternary ammonium salts for sensitive detection by electrospray mass spectrometry. in: Proceedings of the Thirty-Second European Peptide Symposium, September 2-7, 2012, Athens, Greece / George Kokotos, Violetta Constantinou-Kokotou, John Matsoukas (eds). - Athens : University of Athens, 2012, 82-83. ISBN 978-960-466-121-3.
Most important achievement in 2009
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A new method to study N-phoshphorylation of amino acids and proteins by mass spectrometry was deleloped and published: "Thiophosphorylation of free amino acids and enzyme protein by thiophosphoramidate ions", Tomasz Ruman, Karolina Długopolska, Agata Jurkiewicz, Dagmara Rut, Tomasz Frączyk, Joanna Cieśla, Andrzej Leś, Zbigniew Szewczuk, Wojciech Rode, Bioorganic Chemistry, in print (doi:10.1016/j.bioorg.2009.11.002)
Synthesis of the benzimidazole-containing peptides on the solid support
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Development of the new method of the benzimidazole-containing peptides on the solid support.
Discovery of immunomodulatory activity of ubiquitin fragments containing retro-RGD sequence
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Development of a new method of solid-phase synthesis of quinoxaline-containing peptides.
